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Amorphous IV: Hot melt extrusion and powder technology in pharmaceutical industry

12th - 13th June 2012, The School of Science in the University of Greenwich, UK

 
Programme:
Tuesday 12th June:
08.30 – 09.00 Registration
09.00 – 09.10

Introduction
Chairs:  Prof. M. Snowden
  Dr. M. Leane

09.10 – 09.40 Novel Application of HME: Solvent Free Continuous Cocrystallisation (SFCC)
Speaker:
Prof. A. Paradkar, School of Life Sciences, University of Bradford
09.40 – 10.10 Fundamental amorphous characterisation. Thermal and spectroscopic approaches
Speaker:
Prof. M. Descamps, Department of Physics, Université Lille Nord de France
10.10 – 10.40 Design of plant for continuous processing of fine and ultra fine pharmaceutical powders
Speaker:
Prof. M. Bradley, Wolfson Centre, University of Greenwich
10.40 – 11.00 Coffee Break
11.00 – 11.30 Small scale screening for setting up a HME process
Speaker:
Dr. Rod Bottom, Thermo –Fisher Scientific, UK
11.30 – 12.00 Soluplus - an innovative excipient for hot-melt extrusion
Speaker:
Andreas Gryczke, BASF SE, Germany
12.00 – 12.30 Sustained release formulations using HME processing
Speaker:
Dr. Yvonne Cuppok, Gattefosse SAS, France
12.30 – 13.00
Speaker: TBA
13.00 – 14.00 Lunch
14.00 – 14.30 Bioresorbable polymers in melt extrusion - formulation and process design
Speaker:
Dr. Jessica Albers, Evonik Industries AG, Germany
14.30 – 15.00 Application of academic knowledge to late-stage amorphous formulation development.
Speaker: Dr. Clare Rawlinson Malone, Bristol – Myers Squibb, UK
15.00 – 15.30 Scale-Up Approach in HME
Speaker:
Dr. Katharina Paulsen, Thermo–Fisher Scientific, Germany
15.30 – 16.30 Coffee Break
Poster presentation/Exhibition
16.30 – 17.30 Demonstration
a. Hot Melt Extrusion with Eurolab extruder
b. Process analytical technology (PAT) using the FT–IR Antaris probe
19.30 Dinner
   
Wednesday 13th June:
08.55 – 09.00

Introduction
Chairs:  Prof. M. Bradley
  Dr. K. Paulsen

09.00 – 09.30 A review of segregation phenomenon and latest predictive techniques for pharmaceutical powder handling processes
Speaker: Mr. Richard Farnish, Wolfson Centre, University of Greenwich
09.30 – 10.00 Spectroscopic hot-melt extrusion in-process monitoring throughout the entire extrusion barrel
Speaker: Prof. De Beer
, Faculty of Pharmaceutical Science, University of Gent, Belgium
10.00 – 10.30

Melt extruded solid dispersions
Speaker: Dr. Gavin Andrews, School of Pharmacy, Queen's University of Belfast

10.30 – 11.00 The use of NIR to monitor Hot Melt Extrusion
Speaker: Dr. Gareth Barnard, Thermo –Fisher Scientific, UK
11.00 – 11.20 Coffee Break
Poster presentation/Exhibition
11.20 – 11.50 The role of surface and interface in the physical stability of amorphous solid dispersions
Speaker:
Dr. Shen Qi, School of Pharmacy, University of East Anglia
11.50 – 12.20 Solid dispersions and products prepared by using HPMCAS
Speaker: Mrs. Shilpa Mistry , Shin-Etsu Pharma & Food Materials Distribution GmbH, UK
12.20 – 13.00 Co-extrusion of polymer – lipid systems
Speaker: Dr. Dennis Douroumis, School of Science, University of Greenwich
13.00 – 14.30 Lunch
14.30 – 15.30 Demonstrations
c. Measurement of flow properties for use in the design of equipment for reliable handling of cohesive powders
d. Segregation of blended materials through simulated handling processes
15.30 – 16.15 Discussion
16.15 Conference Close
   
   

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